Berberine 60 chap. Nutilab

Nutilab Berberine 60 capsules. Food supplement based on dry extract of agracejo. Berberis vulgaris, or agracejo, which contains in its berries a powerful vegetable alkaloid: berberine. This substance, traditionally used for its immunostimulant, antifungal, antibacterial properties and its ability to regulate intestinal problems, is revealed as a new weapon against type II diabetes and prediabetic states, which have been increasing epidemically for a few years now.

The mechanism of action of berberine is essentially derived from the regulation of AMPK (Adenosine Monophosphate activated Protein Kinase). This proteinkinase, activated by AMP, is a fundamental ubiquitous enzyme involved in the normalization of energy metabolism and in the regulation of food intake and tissue sensitivity. It plays a key role in certain metabolic pathologies such as diabetes, insulin resistance, obesity or complications linked to diabetes.

Berberine, by activating the AMPK, will act on several levels:
.- Improves insulin sensitivity, facilitates intracellular glucose transport, allowing the body to better use both sugars and insulin and, in this way, reduce the rate of glucose in blood;
.- Stimulates the metabolism of fatty acids in mitochondria, reduce the concentrations of circulating lipids in the blood: triglycerides and LDL cholesterol;
.- Favors the extraction of the bloodstream from glucose transporters, allows a notable decrease in blood sugar rates;
– Increasing the production of GLUT4, a glucose transporter found only in muscles and fat cells, will allow a marked improvement in insulin sensitivity.

The combination of these properties allows comparing berberine to the molecule of metformin, a substance widely used in pharmacy for the treatment of type II diabetes and overweight related to glucose metabolism. The most representative studies also deal with the efficacy of berberine compared to metformin in patients affected by type II diabetes, associated or not with dyslipidemia.

Berberine, with classically recognized properties at the cardiovascular, immune and intestinal level, is also shown as an excellent nutritional supplement, very easy to use and well tolerated, in the treatment of type II diabetes, taken at the beginning, or as an adjuvant treatment of the latter.

According to research on berberine, the average recommended dosage varies from 1000 to 1500 mg per day, divided into two or three doses, before the three main meals.

To feel its effects fully, it is desirable to carry out a treatment of at least three months, since its optimal action is observed after two weeks of regular intake.

Apart from the fact that some users have noticed slight temporary constipation at the beginning of treatment, berberine is totally devoid of side effects.

The four main advantages of berberine are therefore summarized as:
.- Notable decrease in blood sugar;
.- Reduction of levels of glued hemoglobin (HbA1c);
.- Rebalancing of circulating insulin rates;
.- Decrease in triglycerides, LDL cholesterol and total blood cholesterol.
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